LOCUS       ERZ1687568.348-NODE-348-length-8573-cov-4.885889 8573 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  ERZ1687568.348-NODE-348-length-8573-cov-4.885889.
ACCESSION   ERZ1687568.348-NODE-348-length-8573-cov-4.885889
VERSION     ERZ1687568.348-NODE-348-length-8573-cov-4.885889
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0beta2
            Run date     :: 2023-04-19 02:04:30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 8573
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..8573
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1731:3141]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1732..3141
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..8573
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..8573
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             complement(356..1570)
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 376.1; E-value: 2.5e-114)"
                     /gene_kind="other"
                     /locus_tag="ctg348_1"
                     /transl_table=11
                     /translation="MAQLHFTLDSDFFVGLFSETKDEAFGKLMEALLNQVLQAESTEQL
                     GANNYERSQERSDYRNGTRTRSLTTRIGKIELQVPRHRNVPFKTSLFENYQRNEQALIT
                     TMMEMVVQGISTRNVKKVTEELCGESFSKSTVSEICKELDVPIKHFKERLLPEHYPFII
                     VDAIYLKVREDHRVKSKALFVAIGINNTGHKEVLGFEVYDSEKVNTWKDFFESLKSRGL
                     RGVDIVISDAHAGLVEAIKESFSGSSWQRCQAHFTRNIIDKCPKKYSTGLASELRDMFN
                     ATTIEEARRLKESIYDEYQDVANEAMVILDEGFEDSITIMALPSKYRIALRTSNIIERE
                     NREIRRREKVIQIFPNTESIIRLIGAVLQDDHNEWSVGHKIFDMKEYYDKLSSIQSNLL
                     KIKVA"
     CDS             1732..3141
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Other_Sactipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg348_2"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     3e-14, bitscore: 42.1, seeds: 13, tool:
                     rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7e-15, bitscore: 44.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-13, bitscore: 39.9,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 3.1e-12, bitscore:
                     35.8, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVFHTFTAGGKRYMFDANTNVIINLKEDLYFELEKYMQSGYKEF
                     TPAIEKLRDRGYLKDRADFEMVHPMDSTLEYSLERCIGTIALQVTQGCNLRCKYCAYSG
                     SYDNRVHSSKRMSKEIAFKAIDFLFDHSIDRDRVSLGFYGGEPLLELDLIKECVKYAKK
                     KSIGKELMFNITSNTTLITDEVLKFLYDNEFSLTVSLDGDRQAHDKNRVFAANGAGTFS
                     VVMQILEKIQTQYPDYMERVHINAVIDPTTDFDCTSNFFSDYKTVKDFYIQANLISEYY
                     RKDEVATDEEYREKFSYEIFKMYLQKLGRLENGSVSKLVSHGFHSLKEIHDKTKMPSSL
                     TIKRDHHSGPCVPGIQRLFVDVEGNLYPCERVSEASKAVRMGHIDTGFDIDKARALLNI
                     GKLTEKECKQCWAFRFCSACAVQADNLEELSAEKKLQNCALIRGHIDNMMRDYCVMRDL
                     GCNFDKEKLFV"
     CDS             3155..4261
                     /locus_tag="ctg348_3"
                     /transl_table=11
                     /translation="MKRKAIIFPYNAECASLVRNRELLLNHEIVACVSPIGYGLQGKDA
                     AYAYGGENTGIVISDKKISEINFDDLLVCESSSDFDTFIMPQVKLAAECGKNVIFLYNI
                     SQQQKKEAEETCKKKNVKCVVLTNRRMDTDKLFEHEIIPLSVPVVFVASVIENTNKFDV
                     QLGLRKFLQEEGYKVSQIGTKEYCELFGFHAIPEFMYANQLSEADKIVWFNRICKSIEL
                     QEKPDIFIIGVPGATMVFNETITNNFGITAFEIANAVRPDTAIMCVPYEGYDSGFLKMI
                     QTSSKYKLDMQVDCFNMANKHFDVARSKEEKKLSFITTGADLVDKRIEDLKRDTEIPIY
                     NSLNVTSALEMYSYIVNKLSESDFGTVS"
     CDS             4279..4551
                     /locus_tag="ctg348_4"
                     /transl_table=11
                     /translation="VDAENIRAKVKKVFFDLFQKDESKIQDSYCTDNFFGSKMGLLPGD
                     VVAYLYAVEKEFNLQIPSSYIQEGKFNTLDNVTNIICEVLQKKDD"
     CDS             4675..6111
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg348_5"
                     /sec_met_domain="Peptidase_S8 (E-value: 8e-14, bitscore:
                     40.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLEIQIAVIDSGLNEKLLDRKKIRNRFEVDENNDFIEERSMSKA
                     SDFLHGTICAIIIEKYCPDAVFNSIRILNQNGTGGVEKLEPALEWCCKNNIKIVNLSLG
                     TTHFKEKDILKKLINRYTYKGLVFVAAISNIGYFTFPASFTNVIGVANVESPLSYSKDY
                     IHLGIDTVTISEHIIMLENKEHKTSPSNSYAAPYICALIANKLSNDKTLDIVKLKRYAK
                     EQSHIEMTVDSYEPDWIYRAYISGRGTMSRAEYYFETVTGVYDEIQGKIDTVIAYSMAE
                     LENLDIRNKNLIYLGHEDIHNIDVQGFIWSKETRQRQIKHNHYQGNGLEVPVVILAVED
                     VIDKFYILTELKRAFANGGYNAYTIGMEPECVLYALEYMPEPVSDIDAWKNFIESQTFY
                     KQSDLVIWCIPVEEQDKYLKVYPDCDVQISLCNEGDINIVRFSFEGEKIEKKISGLIDR
                     KDVEKIYHIIEAKLTEEEDG"
     CDS             6104..7810
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 259; E-value: 1.5e-78)"
                     /gene_kind="transport"
                     /locus_tag="ctg348_6"
                     /transl_table=11
                     /translation="MDNKEAVKRLLLLLGRYKKTIVVIVGCLLVSTGLNLCVPLISRRI
                     MDDGFIGGNKKLLIELVLVSMVIYTINSLIDIVKEKKRVDISAKIQYFLSEQSFSHLMK
                     LRVNYFNNTNYAETLNNINTDINQMTSIADSSVFFVITQAFSMTGGIIGLFIIDFRMTV
                     LVLLFIPIKCVVMKYFAKKQKQIMDEFIKRNQEYAKWFGDTVGGVREVKLFNILDKKHE
                     EFVLNQNNIIEKQKQMNMLGQWNTIIDSIMVQFLSTLLYILGANLVFDMKLSVGSVFAF
                     ITYSAYVTGPISAILNIGYLLSGIIPSTKRYYAFMELEEETDNGKKTDLCPNDLRLQKV
                     SFVYERDKCILKNIDILFAKSSKTAIIGRNGSGKTTIINLLTRMYEPTSGEILLGAENI
                     SELPLPEYRNMVSVVSQQIYLFNDTIRNNICLDKQIDDTVIEAACKDSGLEDFIKEVSL
                     DHVVGQNGAMLSGGQKQKIALARALVHDKPIIIFDEATSNTDAYSEQQINGLLDTRLKD
                     KTVIVITHKKEVLSKVDQIVVLKEGVVADLGRYDDLVGKSDELNVMLEKAE"
     CDS             8212..8571
                     /gene_functions="other (smcogs) SMCOG1198:hypothetical
                     protein (Score: 86.6; E-value: 2.3e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg348_7"
                     /transl_table=11
                     /translation="MYRDTIFQYVKKQYGTIPEYLWNDLPDSAILRNDNGKWYAVFMNL
                     EGFKIGLDTKDRVDIMVVKCKPDMISVMTHMKGFLPGYHMDKSNWITILLDGTVQEAKI
                     LDFLDMSYDLTDGRIE"
ORIGIN
        1 taattgagga ctttactgac tatatcaact tataataatc gatatataat attatgcgct
       61 gaaaggaggt gagaatatga agaagttggt aaagcgtagc gatgttatgc aggaaacatt
      121 ggaggcatat tgcagttgca gttgcagttg ttatggaact tgctcttgta gcactggaca
      181 gacaaataat tcagcagctt tgtttcaggc tagatacacc caattttaca tggactttgt
      241 agcaattcgt atggtgtaag aacatagcaa tgcagcggaa gatgggtatg acaatatgct
      301 ttggagtcaa gtccaaattt gtgtgtaaat tcatctttca gttatgtggt tttatctacg
      361 ctacttttat cttcaagaga tttgactgaa tggagcttag tttatcataa tactctttca
      421 tatcaaagat tttatgacct acactccatt cattatgatc atcttgaagg actgcaccaa
      481 ttaatctaat aatagattcc gtattaggaa aaatctgaat aactttttcg cgtcttctga
      541 tttctctgtt ctcgcgttct attatgttgc tggttcttaa tgctatacga tattttgagg
      601 gaagtgccat gatggtaatg ctatcttcaa acccttcatc aaggataacc attgcttcat
      661 ttgcaacatc ctgatattca tcgtatattg attcttttag gcgacgggct tcttcaatag
      721 tagttgcatt gaacatatct cgcaattcag aagctaaacc agtgctgtat ttttttggac
      781 acttatctat gatatttcta gtaaaatgag cctgacaacg ctgccatgaa gaaccagaga
      841 agctttcctt tattgcttca acaagccctg cgtgtgcatc tgatatcaca atatccacgc
      901 cacgtaagcc acgactttta agactttcaa agaagtcctt ccaggtgttt actttctcag
      961 aatcgtatac ttcaaaaccg agtacttcct tgtgacctgt attgtttatc ccaatagcga
     1021 caaacaatgc tttggacttg acacgatgat cttcgcgaac ttttaaatat atcgcatcaa
     1081 caataataaa tggataatgt tccggtaata aacgttcttt gaaatgttta attggaacat
     1141 caagttcctt acaaatttca gaaacagtag atttagagaa agactctcca cagagttctt
     1201 cagttacttt tttgacattt ctggttgata taccctgcac taccatttcc atcatggttg
     1261 taattaaagc ttgctcatta cgctggtaat tctcgaataa ggaagtctta aatgggacat
     1321 tacgatgtct aggaacttgt aattcaatct ttccgatgcg agtagttaat gaccttgtcc
     1381 gggttccgtt tctgtaatca gaacgttctt gtgaacgttc atagttatta gcaccaagtt
     1441 gttcggtaga ttcagcttga agaacctgat taagtaaagc ttccataagc ttgccaaatg
     1501 cttcatcttt agtttctgaa aaaagtccta caaaaaaatc actatctaat gtaaaatgta
     1561 attgagccat gggtttcatc ctttcaatta tgttttgtgt ggtaacttaa ttataactga
     1621 aagatgagca cttggctctt tttatataga tttgtaattt acaccattat atagacatta
     1681 tctgctttgg gcatattgtc atgcctgttt aataattagg gaggaaatag tatgccggtt
     1741 tttcatacat ttactgctgg tgggaagagg tatatgtttg atgcaaatac aaatgtaatt
     1801 ataaatctta aagaggattt gtattttgaa cttgagaaat atatgcaaag tggatataaa
     1861 gagttcacac cagctataga aaaattaaga gatagaggat atttaaaaga tagagcagat
     1921 tttgaaatgg tgcatccgat ggattctaca ttggaatatt ctttggagcg ttgtataggt
     1981 acaattgcgt tacaagtcac acaggggtgc aatttgcgtt gtaaatattg tgcttattct
     2041 ggtagttatg ataatcgtgt ccatagtagt aagagaatga gtaaggaaat tgcatttaag
     2101 gcaattgatt ttctttttga tcattctata gatcgtgata gggtttctct tggattttac
     2161 ggtggagaac cattacttga attagatttg ataaaggaat gtgttaagta tgcaaagaaa
     2221 aagagcatag gtaaagaatt gatgtttaat ataacttcaa atacaacact tataacagat
     2281 gaagttttga aatttctata tgataatgag tttagcttaa cggtgagttt agatggagat
     2341 cgacaggctc atgataaaaa tagagtattt gctgcaaatg gtgctggtac atttagtgta
     2401 gtaatgcaaa ttcttgaaaa aatacaaaca cagtatccag attatatgga aagagtacat
     2461 attaatgctg ttatagatcc gactacagat tttgattgta ctagtaattt cttttctgat
     2521 tataaaacag ttaaagactt ttatatacag gcaaatctta tttctgaata ttatcgtaag
     2581 gatgaagtgg caacagatga agagtatagg gaaaaattta gttatgaaat atttaaaatg
     2641 tatcttcaaa aattaggaag attggagaat ggaagcgtat caaaacttgt ttcacatggt
     2701 tttcatagtt tgaaggaaat acatgataaa acaaaaatgc catcttcttt aacaataaaa
     2761 agagatcatc attctggacc atgtgtacca ggtatacaga gactatttgt tgatgtagaa
     2821 ggaaacttat atccttgtga acgagtgagc gaagcgtcaa aggcagtaag aatgggacat
     2881 atagatacag gttttgatat tgataaagct agagctttat tgaatattgg aaaattaact
     2941 gaaaaagaat gcaagcaatg ttgggcattt aggttttgtt ctgcttgtgc agttcaagca
     3001 gataatttgg aagaactgtc tgctgaaaaa aagttacaaa actgtgcatt aattcgtggt
     3061 cacatagata acatgatgag agattattgt gttatgagag atttaggatg taattttgat
     3121 aaggaaaaat tgtttgttta gagaaggaga tattatgaaa aggaaagcta taattttccc
     3181 ttataatgca gaatgtgctt ctcttgtacg aaatagagag ttgttgttaa accatgaaat
     3241 tgtggcttgc gtgtctccaa ttggttatgg attacaagga aaagatgctg catatgcata
     3301 tggaggagaa aatacaggga ttgttatctc agataagaaa ataagtgaaa taaattttga
     3361 tgatttgtta gtatgtgagt catctagtga ttttgataca tttataatgc cacaagtaaa
     3421 acttgcagca gaatgtggga aaaatgttat ttttttatat aatatttctc agcaacagaa
     3481 gaaagaagca gaagaaacgt gtaaaaaaaa gaacgtaaaa tgtgttgttc ttacaaatcg
     3541 gagaatggat acagataaat tatttgagca tgaaattata ccattatccg ttccagtggt
     3601 ctttgtagcc agtgttattg aaaatactaa taaatttgat gtgcaattag ggctgagaaa
     3661 atttctgcag gaagaaggat ataaagttag ccagattgga acaaaagaat attgtgagtt
     3721 atttggtttt catgcaatac ctgaatttat gtacgcaaat caattgagtg aagctgacaa
     3781 gattgtatgg ttcaatcgaa tttgtaaaag cattgaacta caggaaaagc ccgatatttt
     3841 tattattggt gtgccgggag ccacaatggt attcaatgaa acaattacaa ataattttgg
     3901 cataactgcc tttgagattg caaatgccgt tagaccagat acagctatca tgtgtgttcc
     3961 atatgaaggt tatgattccg gtttccttaa aatgatacag acatcatcaa aatataagtt
     4021 agatatgcag gttgattgct ttaacatggc aaacaaacat tttgatgtag caaggagcaa
     4081 agaagaaaag aaattgtctt ttataacaac aggtgcagac ttggtggata aaaggataga
     4141 ggatttaaag agagatactg aaatcccaat ttacaactcg ttgaacgtta caagtgcttt
     4201 agagatgtat agttatattg taaataaact gagtgaaagt gattttggaa ctgtaagtta
     4261 agaagggagg agaagaatgt ggatgctgaa aatataaggg ctaaagtcaa aaaagttttt
     4321 tttgatttat ttcagaaaga tgaaagcaag attcaggata gttattgcac tgataatttc
     4381 tttggtagta aaatgggatt attgccggga gatgtagttg cttatttgta tgctgttgag
     4441 aaagaattta atttgcagat tccgtcctca tatatacaag aggggaaatt taatacacta
     4501 gataatgtca caaacattat ttgtgaggta cttcaaaaga aagatgatta aggagtttta
     4561 agactaaaac ggaatctgtt attttatagt caatagtatg taataagggc gtttatcttc
     4621 tatcaaaaag taggttgatt gagatttatg tccttttatt tgtagaggtg cggtatgagt
     4681 cttgaaattc aaattgctgt aatagatagc ggattaaatg aaaagctatt ggataggaaa
     4741 aaaattagaa atcggtttga agtggatgaa aataatgatt ttattgaaga acgctcgatg
     4801 tcgaaagcta gtgattttct tcatggtaca atatgtgcta taataataga aaagtattgt
     4861 cctgatgctg tgtttaacag tattcgcatt cttaatcaga acggaacagg tggggttgaa
     4921 aagctagagc ctgctttaga atggtgttgc aaaaataata taaaaattgt caatcttagt
     4981 ttggggacta cacattttaa agaaaaagat attttaaaaa aactaattaa taggtataca
     5041 tataaaggac tggtatttgt tgcggctata tcgaatatag gatattttac tttcccggca
     5101 agttttacta atgttatagg tgttgcaaat gtggaaagtc ctctatccta ttccaaagat
     5161 tatatacatt tagggataga tacagttaca atttcagaac atataattat gttagaaaat
     5221 aaggaacaca aaacttcacc gagtaacagc tatgcagctc cttatatatg tgcattgatt
     5281 gcaaataaac taagcaatga caaaactctc gatatagtaa aattaaagag atatgctaaa
     5341 gagcaaagcc atattgaaat gacagtggat agttatgagc cggactggat ttacagggcg
     5401 tatatatcgg gcagaggaac tatgagcagg gcagagtatt attttgaaac agttacaggg
     5461 gtgtatgatg aaatacaggg gaaaatagat actgtaatag cttattctat ggcagaatta
     5521 gaaaatttgg atataaggaa taagaactta atatatcttg gtcatgagga tattcataat
     5581 atagatgttc aggggttcat ttggagcaag gaaacaaggc aacggcaaat taagcataat
     5641 cattatcagg gaaatggtct tgaagttccg gtagtgatac tggcagtgga agatgtaata
     5701 gacaagttct atatactcac agaactaaag agggcatttg ctaatggtgg ttataacgca
     5761 tatacaatag gaatggagcc ggagtgtgta ttatatgcat tagaatatat gccggagcca
     5821 gtatcagata ttgatgcttg gaaaaatttt atagagagcc agacttttta taaacagagt
     5881 gatttggtca tatggtgcat tccggtggaa gaacaggata aatatttgaa agtatatcct
     5941 gattgtgatg tacagatcag tctttgcaat gagggagata taaatattgt ccggttttct
     6001 tttgaaggag aaaagattga gaaaaaaata tctggactga ttgacagaaa agatgttgag
     6061 aaaatatatc atattataga agcgaaactg acggaggaag aagatggata acaaagaggc
     6121 tgtaaaaaga ttacttctgt tactaggcag atacaaaaaa acaatagttg taattgtcgg
     6181 ttgtttgctt gtttctaccg ggttaaatct atgcgttccg ctgatcagca ggcgaatcat
     6241 ggacgatggc tttattggcg gaaataagaa attattgata gagctggtct tggtgtctat
     6301 ggtaatctac actataaatt ccctcataga tatagtcaag gaaaagaaac gtgtagatat
     6361 ttcagcaaag atacaatatt ttctttcgga acagtctttt tcacatctta tgaagctgcg
     6421 ggtaaactat ttcaataaca caaactatgc ggagactttg aataatatca acacggatat
     6481 taaccagatg acatctattg ctgacagcag tgtttttttc gtaattacgc aggcgtttag
     6541 catgacaggc ggcataatag gtttattcat aatagatttc agaatgacgg tactggttct
     6601 tctgtttata cctattaagt gtgtggtaat gaaatacttt gcaaaaaagc aaaaacagat
     6661 tatggacgag ttcataaaaa ggaatcagga gtacgcaaaa tggtttggag atactgttgg
     6721 aggggtacga gaagtcaagc tgtttaatat cttggataaa aagcatgagg agtttgtact
     6781 taaccagaac aatattatag agaaacaaaa gcagatgaat atgttagggc agtggaatac
     6841 gataatagat agtatcatgg tacagtttct ttctacattg ttatatatac tgggcgcaaa
     6901 tttagtgttt gatatgaaac tttcagtagg tagtgtgttc gctttcatta catatagtgc
     6961 ttatgttacc ggaccgattt ctgcaatcct aaatatagga tacctgttat cagggattat
     7021 tccgtcaaca aaaagatatt atgcgtttat ggaattggaa gaagaaacgg ataatggaaa
     7081 gaaaacggat ctatgtccaa atgatttgag attgcagaag gtttcttttg tgtatgaaag
     7141 ggataagtgc attttgaaga atattgatat attatttgca aaatccagca agacagctat
     7201 aattgggcgc aatggttcgg gaaagacgac aatcatcaat cttcttacga gaatgtatga
     7261 gccgacaagt ggtgaaatac tgttgggagc agaaaatatt tcagagctgc cattgccaga
     7321 ataccgaaat atggtatcag ttgtgagcca acaaatctat ttattcaatg acacaataag
     7381 gaataatatc tgtctggata aacaaataga tgatacggtg atagaagctg cctgcaagga
     7441 cagcggactt gaagatttta taaaagaggt ttccttagat catgtggtag gacagaatgg
     7501 ggcaatgctc tccggcgggc aaaagcagaa aatagccctt gcaagggcat tggtgcatga
     7561 caagccgatt attatatttg atgaagctac ttcaaacaca gatgcttatt cagaacagca
     7621 gataaacgga ctgcttgata ctcggctaaa agacaaaaca gtgatagtga taacacataa
     7681 gaaagaggta ttgagcaaag tggatcagat cgttgtactg aaggagggag tggttgcaga
     7741 tttagggaga tatgatgatt tggtagggaa aagtgatgaa ctaaatgtta tgttggaaaa
     7801 agcagaataa atataagaaa atcttttcag agtagcaagt cttttttgct tttgggacaa
     7861 aaagtattat ttctggcaga aaatgtgaaa tattattaga tgcttgtcga taaaaaagaa
     7921 aaatagagag aatttgcatc atgcaggtta attctaatta ttctatgtat ggtgtgccgt
     7981 atgaaactta aataggataa tattcctcca tattagtgcg gaatatgctg tacatgaaag
     8041 ttaaaatccc aaagatgcag agatgtatat tatcaacaat tatacatttc tgcatctttt
     8101 tattttgagc attccaatag taatacgcta aatcttaaat aactgtatat gaggaaaata
     8161 tgatatgatt atattcaaat atgaaattac aggatcagag gtatacacag tatgtacaga
     8221 gacactatat ttcaatatgt aaaaaaacaa tatggaacaa ttccagaata tctgtggaat
     8281 gatttaccag atagtgcaat acttcgtaat gacaatggaa aatggtacgc agtatttatg
     8341 aatttggaag gctttaaaat cggattggat acaaaagata gggttgatat tatggttgta
     8401 aaatgtaagc cggatatgat aagtgttatg acacacatga aaggcttcct gccgggatat
     8461 cacatggata aaagtaattg gatcacaatt cttctggatg ggacagtcca ggaggcaaag
     8521 atattagatt ttcttgatat gagttatgat ttgacggatg ggcgaatcga gga
//
