LOCUS       ERZ1687568.63-NODE-63-length-95098-cov-3.988111 13584 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  ERZ1687568.63-NODE-63-length-95098-cov-3.988111.
ACCESSION   ERZ1687568.63-NODE-63-length-95098-cov-3.988111
VERSION     ERZ1687568.63-NODE-63-length-95098-cov-3.988111
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.0.0beta2
            Run date     :: 2023-04-19 02:04:30
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 81514
            Orig. end    :: 95098
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13584
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11359]"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11359
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /neighbourhood="10000"
                     /product="ranthipeptide"
                     /protocluster_number="1"
     cand_cluster    1..13584
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(TIGR03973 or SCIFF or (cds(PF04055 and
                     (TIGR04085 or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /kind="single"
                     /product="ranthipeptide"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13584
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="ranthipeptide"
                     /region_number="1"
                     /rules="(TIGR03973 or SCIFF or (cds(PF04055 and (TIGR04085
                     or SPASM)) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]) and not (TIGR01716
                     or subtilosin or TIGR02111 or TIGR03966 or TIGR04103 or
                     (YcaO or TIGR03604))))"
                     /tool="antismash"
     CDS             567..2525
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 132.9; E-value:
                     2.6e-40)"
                     /gene_kind="transport"
                     /locus_tag="ctg63_72"
                     /transl_table=11
                     /translation="MILSCNHISKSFGTDQIINDCSFHLEEREKAAIIGINGAGKSTLL
                     KIIVGELPADSGNVTVSKGKTLGYLSQHQNLSTDKTIYDELLSVKQDLIDMENTIRSLE
                     IHMKDVTGDELDNLLSQYTRLNHEFEMNNGYAYKSEVTGVLKGLGFGDEDFSLHVNTLS
                     GGQKTRVALAKLLISKPDIIMLDEPTNHLDMDSIAWLENYLLTYNGSVLIVAHDRYFLD
                     KIVTKIIEIDNTAVTVFSGNYTDYAAKKAVLRNMKLKEYLNQQRDIKHQQEVITKLKQF
                     NREKSIKRAESREKMLDKMELVDKPTELNDKMHIRLDPKVVSGNDVLTVKDLSKSFGDN
                     FLFSGLDFEIKRGERVALIGNNGTGKTTILKIINGLIPADYGEITLGSKVTIGYYDQEH
                     HVLDPDKTLFEEIQDAYPDLNNTQIRNTLAAFLFTGDEVFKYIRDLSGGERGRVSLAKL
                     MLSNANFLILDEPTNHLDIVSKEILENALNNYTGTVFYVSHDRYFINTTATRIIELTGH
                     TIVNYIGNYDYYIEKKDILTPKALTDATAAINDSMASSACQTPSSAQGSSKAEWQQSKE
                     EAARLKKLKNELKRTEDKISQTEERISAIDEEYNNPDIASDTAKLVELHNERTSLSEML
                     DELYEKWEELSEELIDK"
     CDS             2582..2857
                     /gene_functions="other (smcogs) SMCOG1132:DNA-binding
                     protein HU 1 (Score: 125.5; E-value: 1.3e-38)"
                     /gene_kind="other"
                     /locus_tag="ctg63_73"
                     /transl_table=11
                     /translation="MNKTELVSAIAEKSELSKKDAEKALNAFIEAVTDELKNGSKVQLV
                     GFGTFETSDRAARTGKNPQTGAEIKIAACKAPKFKAGKALKDSVNA"
     CDS             3011..3487
                     /locus_tag="ctg63_74"
                     /transl_table=11
                     /translation="MEIEKKYLVSELPDNLPQYKCRKIEQGYLSSSPVVRVRMDNDEYY
                     LTYKGKGLLAREEYNLPLTKESYEHLIKKADGNIITKKRYEIPDNSGHTIELDIFEGVF
                     SGTILAEVEFDSVEEAESYNPPAWFKEDVTMNKMYHNSNMSMLDVSHINTGNGE"
     CDS             3489..4763
                     /locus_tag="ctg63_75"
                     /transl_table=11
                     /translation="MKPFIDKEYIKTTLQRLRLAILTLLKWMLCSIASGIVIGLIGAFF
                     HSLLDLAAEIRTAHPWILFLLPISGIIIVFIYRLSGCKSSKGTNLVITAIQSNEEVPLK
                     MTPLIIVSTILTHLCGGSAGREGAALQVGGSLGNAFAKLFNFDDKDTRIMIMCGMSACF
                     SALFGTPVAAAVFSMEVISVGIMYYAALVPCTVAALIASSISSMSGLAATRFTVEEIPQ
                     FGIPNGIKFFILSLIFAVASILLCVVLHKTSHFFTAHFENQYVRIIVAAVLVIIMRFLF
                     GTTDYLGAGTDIIARSFVEQSAWYVFLLKMIFTAVTLGGGFKGGEIVPTLFVGATLGSF
                     LAPIFGLPTGICAACGMVAVFCGVTNCPLTSLLLSIEMFGSESLKYCLLCIALSYLLSG
                     YYSLYNSQKIMYSKYRTEFINRHSS"
     CDS             complement(4885..5913)
                     /locus_tag="ctg63_76"
                     /transl_table=11
                     /translation="MKKKLMALILCMVMALGLTACRMPSDGKRDADNSDVTQSQTQSYE
                     AKDITVAALKGPTAIGMVKLMEDSKEKKTANNYDFKIAASADEFSSLLIKGDVQIAALP
                     CNAAATLYNKSNGKIKVLGINTLGVLYIVEKGNTVQNVADLKGKTIYTTGKGTTPEYTL
                     KYLLKKAGLDAEKDVNIEFKSEASEAATMLASSDSGAVAMLPQPYVTTVMAANSDVRIA
                     LDVTKEWENLSTDGSTVVTGVIAVNADYYEKNKAAVAKFMEEYENSVDFVNSNVDTAAE
                     YVEEFGIFKAAVAKKAIPYCNITFIKSNEMKTRINQYLTILYESNPSSVGGSMPDNNFY
                     AE"
     CDS             complement(5944..7650)
                     /locus_tag="ctg63_77"
                     /transl_table=11
                     /translation="MSKWMVYAKKADFKAIAARYGIDQVIARIIRNRDVCTNEEIDMYL
                     GGDISSMHDAHLLKDADKAADIIIDKINHRKHIRIVGDYDIDGVCSVTILLKGLKRAGA
                     DVDYTVPDRIADGYGINENIINHAIEDGIDTIVTCDNGIAAIPQINYAKDNNMTVIVTD
                     HHDIPFKEENGEKVFLESDADAIVNPKQKECKYPFKMLCGATVAYKIIEIIYERLNLNP
                     EDLNEYRQLAAIATIGDVVDLEDENRILVKFGLSTLKNTKNTGIRALADACQIDIASLS
                     SYHIGFVIGPCLNAGGRLETARHAVSLLMEENPGEARVKAEKLRSLNEERKDMTEKEAA
                     KAIDMVENTELINDNVLVVYLPECHESVAGIIAGRVKEYFYRPTFVITDAAEGAKGSGR
                     SIEGYNMFEEITRCGYLLNKFGGHPMAAGISLDKENIDEFRWQLNHNQKLTKEQLTPVT
                     WIDVPMPLGYAGFPLIEQLKLLEPFGKGNEKPVFADKNLRVRQASIIGKNRNVLKMVLE
                     DANAYSYDAIMFRADSMNVPKREQNISIVYYPSINEFNGKKTIQFVVTEWK"
     CDS             complement(7729..10008)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035:MMPL domain-containing transport protein (Score:
                     48.1; E-value: 8.3e-15)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg63_78"
                     /transl_table=11
                     /translation="MTKKEGSFTKKMKYSKAKKIVYSIVILAMIIGFTLISVFGIDENG
                     SGSAKDINLGLDLAGGVSITYEIQEDNPSSQDIKDTIAKLEKRVEGKSTESQVYEAGDK
                     RITVEIPGVTDANAILEELGTPGSLEFLDSTGYTAWSKGEEYTPLLTGSDVKGAQAYTD
                     TSSSSSTSFGVQLTFTDDGAAKFEQATRDNLNKIIYIVYDGQVISYPTVESVISGGTAS
                     ITNMESFESADNLAVFIRIGSIPLTLNEVSSNVVAAQLGHNAIRTSVIAAAIGLIVLCI
                     FMIVSYRIPGVVATLALWIYTALVLVLVSVYDITLTLPGLAGIILGIGMAVDANVVIYS
                     RIREEIGAGRSVESAIQAGYSKATSAIVDGNITTLIAAVVLYIFGTGPIKGFAMTLALG
                     IVVSMFTALVITRVIMKLFYNFGITDVKWYGRTIHTKKFNFLGIRKWCFIGSAVVILAG
                     FIGMAGFKASGNRALNYSLEFVGGTTTTYTFQQEYSQEQIENEIIPVIRQAAGITEVQQ
                     QKVKDSTKVTFKTTDLTLDQREAAEEAVKAKFPIQDGTIVESDTIGSSVSATMKQSAFI
                     SVIIATICMLIYIFIRFRDIKFALAAVIALVHDCLVVLAFYALARVQVGTTFIACMLTI
                     VGYSINSTIVIFDRIRESLKNANRKTNIAELVNEAIGNTFTRTFNSSLTTFIMLLSLFI
                     FGVTSVREFALPLMVGVIAGAYSSVCITSALWYVLGGKKIGAQAEEAAKEEKKKKAAIG
                     EDGSQV"
     CDS             complement(10001..11359)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: Ranthipeptide_rSAM_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: TIGR04085"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ranthipeptide: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg63_79"
                     /sec_met_domain="Ranthipeptide_rSAM_RRE (E-value: 2.7e-36,
                     bitscore: 116.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.9e-07, bitscore: 23.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.4e-16, bitscore: 51.5,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 7.9e-14, bitscore: 44.7,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 1.5e-19, bitscore:
                     62.6, seeds: 281, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVHQYKNNGYNIVLDVNSGSVHVVDDMVYDIIEQYENHSLDEIIE
                     LLENKYPESDVREAYNEIEQLKEDGQLFTEDIYEPYIDSFKDRPTVVKALCLHIAHDCN
                     LACKYCFAEEGEYHGRRAMMSFEVGKKALDFLVANSGSRRNLEVDFFGGEPTMNFEVVK
                     QLVEYGRSLEEANNKKFRFTLTTNGILLDDDILEFANKEMGNIVLSIDGRKEINDLMRP
                     TRNGHGSSYDIIMPKFKKVAESRNQNNYYVRGTFTHNNLDFANDVLHLADEGFEQISVE
                     PVVAQPTDDYAIRPEDVPFICEQYDLLAKELVKRKKAGNGFNFFHFMIDLNGGPCVAKR
                     LSGCGSGCEYLAVTPWGDFYPCHQFVGNEDFLMGNVDDGITRTDIRDMFKNSNVYSKEK
                     CKNCFAKFYCSGGCAANSYNFHGNINDAYDIGCDLQRKRIECAIMIKAALAND"
     CDS             complement(11671..12639)
                     /locus_tag="ctg63_80"
                     /transl_table=11
                     /translation="MDSFIYSINSTVPIFLVMILGWVIKQLGIIDDNFASKANKYVFKV
                     ALPVLLFRDLSATDFKSQFDAKFVIYCMVVTILMFSIIWILTEIFMKDESMKGAFVQAS
                     FRSSAAILGMAFIQSMYSSTGMAPLMIVAAVPLFNIFSVIVLTFKAVPENADGKAAEKD
                     SASNIKKACINIARNPIIIGIVLGFLASVAGLKQPVIMQKTIQSVAQTATPVALICIGA
                     GFEGSKAIKKIKPTLIATFIKLVGIAAIAIPVAVMMGFRNQELVAILIMTASPSTVTCY
                     IMAKNMDNDGVLSSSIIVLTTLLSSITLTGWIFVLRSLGLI"
     CDS             complement(12661..13458)
                     /locus_tag="ctg63_81"
                     /transl_table=11
                     /translation="MKKVLTIAGSDCSGGAGIQADLKTMMAHKVYGMSAITSLTAQNTT
                     GVYGISDVTPDFLANELECIFDDIFPDAVKIGMVSNSALIRTIADKLKKYKPKNIVLDP
                     VMVSTSGSRLLEEEASASLINILMPLADIITPNIPEAEVLSSMKISKSEDMVEAAKVIS
                     DKLDGRTAVLVKGGHDLNTANDLLYCDERAVWFEGERINNDNTHGTGCTLSSAIACNLA
                     MENDMASAVENAKKYISGALKDGLNLGKGSGPLNHAFWLDINR"
ORIGIN
        1 tctcctgtcc accatatacc ggaagcactt ttatgtcgct catatatttt gcaagttttc
       61 tgatttcttc tgcaacctgg actgcaagtt ctcttgtcgg gcagagtatt actgcctgaa
      121 gtttctttaa atcaggatct attttttcga gaacaggaat agaatatgct gccgtctttc
      181 ctgtacctgt ctgtgcctgt ccgaccacat ctcggtcgtc cataataacc ggaatagctg
      241 aagcctgaat aggagatgcc tcttcaaacc ccatatcttc aacagctctt aatattctct
      301 catctaaatt taattcttca aatttcatta attctccatt cctgctctgt aaaaagcaat
      361 ctttataatc gatttatttt acacaattat gcttataaag tcaaaatgtt tattattaca
      421 tacaattcag acactcaata tatccattgc cttcctatgc atattgcaaa taaagcattt
      481 tccatttata ataaaatatt agtgtggcag acaagtcttt tacctgtcac catgtataag
      541 caaattttca aaggacggat ataaaaatga ttttatcatg taaccatata agcaaatcgt
      601 ttggcactga ccagattata aatgactgct catttcacct tgaagaacgt gaaaaagctg
      661 ccataatcgg aatcaatggt gccggaaaat ctactctttt aaaaatcatt gtcggtgaac
      721 ttcccgctga ttcaggaaat gtgactgtct ccaaaggaaa aactctcggt tatctttcgc
      781 agcaccagaa tctctcaact gacaagacta tatatgatga acttctgtct gttaaacagg
      841 atttaattga tatggaaaat actatccgca gtctcgaaat acatatgaaa gatgttacag
      901 gcgatgagct tgacaacctg ctttcacagt atacaaggct taatcatgaa tttgagatga
      961 ataacggata tgcatataaa agtgaagtta ccggtgtcct taaaggtctt ggatttggcg
     1021 atgaggattt ttctcttcat gtaaacacac tctcaggcgg tcagaaaacg cgtgttgcac
     1081 ttgcaaaact gctcatatca aagcctgaca tcatcatgct tgatgaacct accaaccatc
     1141 ttgatatgga ttctattgca tggcttgaaa attatcttct cacgtataat ggaagcgtct
     1201 taatagttgc acatgacagg tattttcttg ataaaattgt cacaaagatt atcgagattg
     1261 acaacactgc cgtcactgta ttttccggca attatacaga ctatgctgcc aaaaaagctg
     1321 ttcttcgcaa catgaaatta aaagaatacc taaaccagca gcgtgatatc aaacaccagc
     1381 aggaagtaat cacaaaactg aaacagttca accgtgaaaa atcaatcaaa cgtgccgaaa
     1441 gccgtgaaaa aatgcttgac aaaatggaac ttgtcgataa gccaacagaa ttaaacgaca
     1501 aaatgcatat acgccttgat cctaaggtgg taagcggcaa tgacgtatta actgtcaaag
     1561 acctttcaaa aagttttggc gataactttt tattttcagg tcttgacttt gaaataaaaa
     1621 gaggcgaacg cgttgccctc atcggcaata acggaacagg caaaacaaca atacttaaaa
     1681 taattaacgg tttaattcct gctgattatg gtgaaatcac tctcggttca aaagttacaa
     1741 tcggatatta cgaccaggaa catcacgttc tcgaccctga taagactctg tttgaggaaa
     1801 ttcaggatgc ttatcctgac cttaacaaca cacagataag aaacactctc gccgcatttt
     1861 tatttaccgg tgacgaagta tttaagtata tcagggattt gagcggtggc gaacgtggac
     1921 gtgtatcact tgcaaaactt atgctttcaa acgccaactt tctgattctt gatgagccaa
     1981 ctaaccatct tgatatagtt tcaaaggaaa ttcttgaaaa tgcacttaat aattacaccg
     2041 gaactgtttt ttatgtctca catgacagat attttatcaa cacaacagcc acaagaatta
     2101 ttgaacttac agggcataca attgtaaatt atatcggcaa ttacgattat tatatcgaaa
     2161 aaaaggatat acttacacca aaagcactta ctgatgctac agctgccatt aatgacagca
     2221 tggcgtcatc agcctgtcag acaccgtcat cagcacaggg gtcttcaaag gcagaatggc
     2281 agcagtcaaa agaagaagct gcaagactta aaaaacttaa aaatgagctg aaacgcacgg
     2341 aagacaaaat cagccagact gaagaacgca tcagtgcaat tgatgaagaa tataacaatc
     2401 ctgatattgc aagcgacaca gcaaaacttg tcgaacttca caatgaacgc acttctctct
     2461 cggaaatgct tgatgaattg tacgaaaaat gggaagagct atccgaagaa cttattgaca
     2521 aataagtcct tatggagtat aaagaagtat aatatattta tctaaggagg atgttcctat
     2581 aatgaacaaa acagaattag tatctgctat cgcagaaaaa tctgaattat caaagaagga
     2641 tgctgaaaag gcattaaacg cttttattga ggccgtgaca gatgaattaa agaatggctc
     2701 aaaagtacag ctcgtaggtt ttggtacatt tgagacttct gacagagcag caagaacagg
     2761 caagaatcca cagacaggtg ctgagattaa gattgctgca tgcaaggctc ctaagtttaa
     2821 ggctggtaag gctttaaagg attctgtaaa cgcttaatca tatagtataa tctataataa
     2881 gcaagattta agaccatgat gtgtttgcat tttctaatat gctctcccag catggtctta
     2941 tatttttgca gcatacaggc aaagtccgcc actttgccat ttaataaata taaaatggag
     3001 aatatctgca atggaaatcg aaaaaaaata tcttgtatcg gaacttcctg ataatctgcc
     3061 acaatacaaa tgccgtaaaa tcgagcaagg ttatctttca tcctctcctg ttgtacgtgt
     3121 cagaatggac aacgacgaat attatcttac atacaaggga aaaggtttac tcgcaagaga
     3181 agaatataat cttcctctca caaaagaatc atatgaacat cttatcaaaa aggctgatgg
     3241 caatataata acgaaaaaac gctatgaaat tcctgataac agcggacata ctattgagct
     3301 tgatatattt gaaggtgttt tcagcggaac aatccttgcc gaagttgaat ttgattctgt
     3361 tgaagaagcc gaaagctaca atccaccggc atggtttaaa gaagacgtaa caatgaacaa
     3421 aatgtatcat aacagtaata tgagcatgct tgatgtaagc catattaata ctggaaacgg
     3481 agagtaaaat gaaacctttt attgataaag agtatattaa aacaactttg cagagactgc
     3541 gtcttgccat ccttactctc ttaaagtgga tgttatgctc gattgcatca ggtattgtaa
     3601 tcggtcttat aggagctttt ttccattcac tcctcgactt ggccgccgaa ataaggactg
     3661 cacatccatg gatactgttt ttgcttccaa tatcaggtat tatcatagtt tttatatacc
     3721 gcctttccgg atgtaaaagc agtaaaggca caaaccttgt tataacagct attcagtcca
     3781 acgaagaagt tccgctaaaa atgacacctt taattattgt atcgacaatc cttactcacc
     3841 tatgcggtgg ttcagcagga cgagaaggtg cagcacttca ggtcggcggt tctttaggca
     3901 acgcttttgc aaagctattt aactttgatg acaaagacac tcgaataatg ataatgtgcg
     3961 gaatgagtgc atgcttctct gcacttttcg gaactcctgt agccgcagct gttttttcaa
     4021 tggaagttat cagcgtcggc ataatgtatt atgcagcact cgttccatgt actgttgctg
     4081 cacttatagc aagcagcatt tcctcaatgt caggccttgc cgccacacgt tttactgtag
     4141 aagaaatccc tcagtttggt attcctaatg gtataaaatt tttcatcctg tcactcatct
     4201 ttgcagtagc aagcatactt ttatgtgttg ttttgcacaa aacctcacat tttttcactg
     4261 ctcattttga aaaccagtac gttcgtatca tagttgcagc cgtgttggtt attattatga
     4321 gatttttatt cggcactact gattatcttg gtgccggtac agacataatt gcacgcagct
     4381 ttgtcgaaca gagtgcatgg tatgtattcc ttttgaaaat gatttttaca gctgtcactc
     4441 ttggcggcgg atttaaaggc ggcgaaattg ttcctacact ttttgtcggt gctacacttg
     4501 gaagcttcct cgctccgata ttcggacttc ctacaggcat atgtgctgca tgcggcatgg
     4561 ttgcagtatt ctgcggcgta actaactgcc ctctcacatc tctgcttctc tcaatagaga
     4621 tgtttggcag cgaaagtctg aaatactgcc tgttatgtat tgctttaagc tatctgctct
     4681 caggttatta tagtctctat aacagccaga aaatcatgta ttcaaaatac agaaccgaat
     4741 tcattaacag acattcttct taaaataaca taaatcactt ctttagtgca ttataaaaaa
     4801 ccggtatcag acattatcga ttttcatctt ttgtctgata ccggctttta tttaatttgt
     4861 ttattccgac tgaaaacaat ctatttattc cgcataaaaa ttgttatccg gcatactgcc
     4921 gcccactgat gaagggtttg actcataaag tattgtaaga tactgattta tgcgtgtttt
     4981 catttcattt gacttgataa atgtgatatt acaatatgga attgctttct tggcaactgc
     5041 cgctttaaat ataccaaatt cctcaacata ttctgctgct gtatcaacat ttgaatttac
     5101 aaaatcaact gaattttcat actcttccat aaatttggca actgctgctt tattcttttc
     5161 ataataatct gcattaacag ctataactcc ggtaacaaca gtgcttccgt ctgttgaaag
     5221 attttcccat tcttttgtta catcaagtgc aattcttaca tcgctgtttg ccgccataac
     5281 agttgtaaca tatggctgcg gaagcattgc aactgcacct gaatctgatg aagcaagcat
     5341 tgttgctgcc tctgaagcct ctgacttaaa ttcaatattc acatcttttt cagcatcaag
     5401 ccctgccttt ttcaaaagat atttaagtgt atactccggt gttgtacctt ttcctgttgt
     5461 ataaattgtt tttcctttta aatcagctac attctgcacc gtgtttcctt tttcgacgat
     5521 ataaagcaca ccgagtgtat ttatgccaag caccttgatt ttgccattgc ttttgttgta
     5581 aagtgttgca gccgcattac aaggcaatgc tgctatctgc acatctcctt ttatcagaag
     5641 cgaactgaat tcgtcagcag atgcagcaat cttaaaatca taattattgg ctgtcttttt
     5701 ttcttttgaa tcttccataa gcttaaccat tccaatcgct gtaggtccct tcaaggcagc
     5761 aactgtaata tcttttgctt catagctctg tgtctgtgat tgtgtcacat cactgttgtc
     5821 tgcatctctt ttaccgtcag aaggcatccg gcacgcagta agcccaagtg ccattaccat
     5881 acataaaatc aatgccatga gtttcttttt cattttctct ttctcctttt caacttccct
     5941 attttatttc cactccgtaa caacaaactg aatagtcttt ttcccattaa attcattgat
     6001 ggatggataa taaacaattg aaatattctg ctccctcttt ggaacattca tgctgtcagc
     6061 acgaaacatt atagcatcat acgaatatgc atttgcatct tccagcacca tttttaaaac
     6121 attcctgttt tttcctatta ttgaagcctg tcttacccta agattcttat ctgcaaatac
     6181 aggtttttca tttcctttgc caaatggttc caaaagcttt aactgctcaa taagcggaaa
     6241 tcctgcataa cccagaggca ttggaacatc tatccatgta acaggtgtaa gctgctcttt
     6301 tgtaagcttc tggttatgat taagctgcca cctgaattca tcaatatttt ctttgtcaag
     6361 tgatattcct gccgccatcg gatgacctcc gaatttattt aaaagataac cacatcttgt
     6421 tatctcctca aacatgttgt agccctctat ggaacggcct gaaccttttg caccctcagc
     6481 tgcatcagtt ataacaaatg tcggtctgta aaaatattct ttcactcttc cggcgattat
     6541 tccggcaaca ctctcatgac actccggaag atacacaact aaaacattat cattgataag
     6601 ttccgtattt tccaccatat caatagcttt tgcagcttct ttttctgtca tatccttacg
     6661 ttcttcatta agtgagcgta acttttctgc cttgactctg gcttcgcctg gattttcttc
     6721 cataaggagg cttaccgcat gccttgctgt ttcaaggcgt ccgccagcat taagacatgg
     6781 gcctataacg aaaccaatat gatatgatga aagagaggct atatcaatct gacatgcatc
     6841 tgccaaagca cgtattcctg tatttttcgt gtttttcagt gttgaaagtc caaattttac
     6901 aagaatcctg ttttcatctt caaggtcaac cacatctccg attgtggcaa tagctgcgag
     6961 ctgcctgtat tcatttaagt cttccggatt aagattaaga cgctcataaa taatctctat
     7021 aattttgtat gcaactgttg caccacaaag cattttaaaa ggatacttac actctttctg
     7081 ctttggatta actatcgcat ctgcatcaga ttccagaaat actttttctc cattttcttc
     7141 cttaaaaggt atatcgtgat ggtctgttac aatcactgtc atgttattgt ctttagcata
     7201 atttatctgt ggtattgctg caattccatt atcacatgtc acaattgtat ctatgccatc
     7261 ttcaatagca tgattaataa tattttcatt aattccatat ccgtcagcta ttctgtcagg
     7321 cactgtgtaa tctacatctg ctcctgctct tttaagaccc tttaataata tcgtaacaga
     7381 acatacgccg tcaatatcat aatctccaac tattcttata tgttttctat gatttatttt
     7441 gtcaataata atatccgccg ctttgtctgc atcctttaat aaatgtgcat catgcatact
     7501 tgatatatct ccgccaagat acatatcaat ctcttcattc gtgcatacat cacggtttct
     7561 tataattctg gctataacct ggtcaattcc atatctggcc gcaattgctt taaagtcagc
     7621 ctttttggca taaaccatcc atttactcat aatttttctc cataaaagaa aagggagagc
     7681 aagctccccc tttcaataat cactcaatat tccaattgaa tatacttttt aaacctgtga
     7741 gccatcttcg ccaatagcag cttttttctt cttttcttcc tttgctgctt cctcagcctg
     7801 tgctccgatt ttcttaccgc caagaacata ccataatgca cttgtaatac atactgatga
     7861 atatgcaccg gcaattacac caaccataag tggaagtgca aattctctta ctgatgtcac
     7921 gccaaaaata aataatgaaa gaagcatgat aaatgttgta agagatgaat tgaatgttct
     7981 tgtaaatgta ttaccaattg cttcatttac aagctcagca atattagtct ttctgttagc
     8041 attctttaag ctttctctga ttctgtcgaa aatgacaatt gtactgttga ttgaataacc
     8101 aacaatagta agcatacatg caataaatgt tgtacctacc tgaactcttg caagggcata
     8161 gaatgcaagt acaacaagac agtcatgaac aagtgcgata actgcagcaa gtgcaaattt
     8221 gatatccctg aatctgataa agatataaat aagcatgcag attgttgcaa taataactga
     8281 aataaatgca ctctgcttca ttgtagcact aactgaagaa ccgattgtat ctgattcaac
     8341 aattgttcca tcctgaatag ggaacttagc ttttacagct tcttccgctg cttctctctg
     8401 gtcaagtgtg agatctgttg tcttaaatgt tacttttgtg ctgtctttaa ctttctgctg
     8461 ctgtacttct gtaataccgg cagcctgtct gattacagga ataatttcat tttcaatctg
     8521 ttcctgtgaa tattcctgct ggaatgtata agtagttgtt gtaccaccta cgaattcaag
     8581 actgtaatta agagctctgt ttcctgatgc cttaaatcct gccataccga taaaaccagc
     8641 aagaataact actgcagaac cgataaaaca ccattttctg ataccaagga aattaaactt
     8701 cttagtatga atagttcttc cgtaccattt tacatctgta ataccaaagt tgtagaaaag
     8761 cttcatgatt actcttgtga ttacaagtgc tgtaaacatt gatacaacaa taccaagagc
     8821 aagtgtcatg gcaaatccct tgataggacc agtaccaaat atgtagagaa ctactgctgc
     8881 aataagagtt gttatattac catcaacaat tgctgatgta gcttttgaat aacctgcctg
     8941 aatagccgac tcaacgcttc ttcctgcacc gatttcctca cgtattcttg aatagataac
     9001 tacgttggca tccacagcca tacctatacc aagaataata cctgcaagac ccggaagtgt
     9061 aagtgttata tcatatacgc ttacgagtac aagtacaagt gctgtgtaaa tccataatgc
     9121 aagtgttgca acaacaccag gaattctata cgaaacaatc ataaaaatgc aaagtacaat
     9181 aagaccgatt gcagctgcaa taacacttgt acggattgca ttatgtccga gctgtgcagc
     9241 aactacatta gaacttacct cgttaagtgt aagaggaatt gaacctattc ttatgaatac
     9301 tgcaagatta tcagctgatt caaatgattc catatttgta atagaagctg ttccgcctga
     9361 aattacagac tcaactgtcg gatagcttat tacctgtcca tcataaacaa tatagataat
     9421 cttattaagg ttatctcttg ttgcctgctc aaactttgct gctccatcat cagtaaatgt
     9481 aagctgaaca ccaaatgatg ttgatgatga tgagcttgta tctgtataag cctgtgctcc
     9541 ctttacatca gaacctgtaa ggagtggcgt atattcctct ccctttgacc atgctgtata
     9601 tcctgtactg tcaagaaatt ccaaagaacc aggtgtaccg agctcttcaa gaattgcatt
     9661 agcatctgta acaccaggaa tctcaactgt tattctcttg tcgcctgctt cgtaaacctg
     9721 tgattctgta ctcttaccct ccacacgttt ttcaagcttt gcgattgtat ctttgatatc
     9781 ctgactgctt ggattgtcct cctgtatttc ataagtaata cttacaccac cggcaaggtc
     9841 aagtccaaga ttaatatctt tggcacttcc tgaaccattt tcgtcaatac cgaaaacaga
     9901 aatcagtgta aagccgataa tcatagcgag tatcacaatt gaatacacta tttttttagc
     9961 tttgctgtac ttcatttttt tagtaaaact cccttctttt ttagtcattt gcgagtgctg
    10021 ctttaatcat aatagcacac tcaattcttt ttctctgtaa gtcacagccg atgtcatatg
    10081 catcgttaat attcccatgg aaattgtaag aatttgcagc acacccacca ctacaataaa
    10141 acttagcgaa acaattctta cacttttcct tagaataaac attactattc ttaaacatat
    10201 cgcgtatatc tgttctggta ataccatcat ccacattacc cataaggaaa tcttcatttc
    10261 ctacaaactg atgacatgga taaaaatcgc cccatggagt caccgcaaga tattcgcatc
    10321 ctgaaccaca tcctgaaagt ctttttgcaa cacatggtcc gccgtttaag tctatcataa
    10381 aatggaaaaa gttaaatccg ttaccggcct ttttacgctt tacaagctct tttgcaagta
    10441 aatcgtactg ttcacatata aaaggtacat cttccggtct tatcgcataa tcatctgtag
    10501 gctgtgctac aacaggctcc accgaaatct gttcaaatcc ttcatcagca agatgaagaa
    10561 catcatttgc aaaatcaaga ttattatgtg taaatgtacc tcttacataa taattattct
    10621 ggtttctgct ctctgctacc ttcttaaact taggcattat aatatcatat gaactgccat
    10681 gtccgtttct tgtagggcgc attaaatcat taatttcctt acgtccgtca atacttaaaa
    10741 caatatttcc catctcttta ttggcaaatt caagaatatc atcatcaaga agaattccat
    10801 tagttgtaag cgtaaatctg aactttttat tattagcctc ttcaagactt cttccatact
    10861 ctacaagctg ctttacaacc tcaaagttca ttgtaggctc gccgccaaag aaatcaactt
    10921 caagattgcg tcttgaaccc gaattagcaa ctaaaaagtc aagtgctttc ttgccgactt
    10981 caaagctcat catagctctt cttccatgat attctccctc ttcggcaaaa caatacttac
    11041 aggcaagatt acagtcatgt gcaatgtgca gacataatgc ctttacaact gtaggtctgt
    11101 ccttaaatga atctatatat ggttcataaa tatcttctgt aaagagctgt ccatcttctt
    11161 ttaactgctc tatctcatta tatgcttcac gcacatcact ttcaggatac ttattctcca
    11221 gaagttctat gatttcatcc agtgaatggt tctcatactg ttcaataata tcgtatacca
    11281 tatcatctac aacatgaacc gaaccactgt ttacatcaag aacaatatta tatccgttat
    11341 ttttatactg gtgtaccatt tgttctccgt tcctgtccaa atctttttta aagaaaataa
    11401 gagcgtgtcg aaaatgctta acacgctctc cttttctact gattactgct gtaacacaac
    11461 aactgttact tagttattct tattctcaca gctctggttg ccgactgtac atgatgtctt
    11521 acatgctgac tggcatgatg tctgacactc gccacatccg ccatgcttca ttgtatcttt
    11581 taatacacga ttgctgattg tcttaatatg cttcacgaca attcctcctt ctgtttttaa
    11641 actagcgata attataacat gtccttctct ctaaatcaag cccaaactcc taagcacaaa
    11701 aatccaccct gtcaatgtta tgcttgaaag aagcgttgta agaacaataa tgcttgaaga
    11761 aagaacacca tcattatcca tattctttgc cattatataa catgttactg ttgatggaga
    11821 ggcagtcatt ataagaattg cgacaagttc ctgatttctg aatcccatca taactgccac
    11881 cggtatagct atggccgcta ttcctaccaa tttgataaat gttgctataa gcgtaggttt
    11941 tatcttcttt atagccttgc tgccctcaaa tccggcaccg atacatatta aagcaaccgg
    12001 ggtcgctgtc tgggcaaccg actgaatcgt cttctgcatg ataaccggct gtttaagccc
    12061 tgcaaccgac gcaagaaatc caagtacaat accgataata atcggatttc tggctatatt
    12121 aatacatgct ttctttatat ttgatgcact atctttttca gctgctttgc catctgcatt
    12181 ctcaggtact gctttaaatg taagaacaat aacagaaaat atattaaaca gcggcacggc
    12241 agcaacaatc ataagaggtg ccattcctgt gcttgaatac atgctctgta tgaaagccat
    12301 gccaagaatt gccgcactgc ttcgaaatga tgcctgaaca aatgccccct tcatagattc
    12361 atctttcata aaaatctctg ttaaaatcca tattattgaa aacataagta ttgtaaccac
    12421 catacagtaa atcacaaact ttgcatcaaa ctggctttta aaatccgtag ctgacaaatc
    12481 acggaataaa agcaccggaa gtgccacctt aaatacatat ttatttgctt tagaagcaaa
    12541 attgtcatca attataccaa gctgttttat aacccatcca agtatcatga caagaaatat
    12601 cggaacagtt gaattaatgc tgtatataaa actatccata ttattttcct ctgtttttta
    12661 ttatctgttg atatcaagcc agaaagcatg atttaaaggt ccgctgcctt ttccaagatt
    12721 aagtccgtcc tttaaagcac ctgatatata tttctttgca ttttctacag cagatgccat
    12781 atcattttcc attgcaagat tacatgctat cgcagacgat aatgtgcagc ccgttccatg
    12841 agtattatca ttatttattc tctcaccctc aaaccagact gctctttcgt cacaataaag
    12901 cagatcattc gccgtattaa gatcatgtcc gccttttacc agcaccgctg tcctgccatc
    12961 aagcttatcg cttataactt tagcagcttc caccatatct tctgacttgc ttatcttcat
    13021 tgatgataaa acctcagcct caggtatatt tggcgtaatt atatctgcaa gcggcataag
    13081 aatgttaatc aatgatgcac ttgcctcttc ttccaaaagt cttgacccgc ttgttgaaac
    13141 cataaccggg tccaaaacga tatttttcgg tttgtatttt tttaatttat cggcaatagt
    13201 ccttataagt gctgaattgg ataccattcc gatttttact gcatcaggaa atatatcatc
    13261 aaatatacat tcaagttcat ttgcaagaaa atcaggtgtc acatcactta ttccatatac
    13321 gcctgtagta ttttgtgctg tgagtgacgt aatggcactc atcccataga ctttatgtgc
    13381 catcatagtc tttaaatcag cctgtattcc ggcaccaccg ctgcaatcac ttccggcaat
    13441 cgttaaaact ttcttcatat agcctccttt ttaattcgcg gcattcacca gttttaccat
    13501 gctctcatga attccggcca gccacctgca aaatcgggta ggaggtagat aattatttta
    13561 tctaccgacc tcccacacca ccgt
//
